As a guest conductor, Wyers has led high school honor choirs and all-state choruses in New York (Alice Tully Hall, Lincoln Center), Georgia, Missouri, Louisiana, Connecticut, Nebraska, Texas, Washington, Alaska, Idaho, and Vancouver, Canada. She has conducted semi-professional ensembles across the United States and in Germany, the Netherlands, Estonia, and Sweden. Wyers is in demand for Zoom lectures during the pandemic with Res Diversa Chamber Choir (Chile), Western Washington University (a three-week composition crash course), University of Iowa, Northern Illinois University, Montana State University, and with the Mastersingers of Milwaukee (Wisconsin). Her appearance with Kansas and Nevada All-States will take place during the 2020-21 academic year.
Wyers is a leading national figure in the application of Laban movement theory for conductors. She has served as guest lecturer in conducting at Sweden’s Örebro Universitet, European Festival of Church Music (Germany), Latvian Academy of Music, Eastman School of Music, Ithaca College, Westminster Choir College, University of Iowa, Hobart and William Smith Colleges and Portland State University.
Wyers’ choral works are published by Santa Barbara Music Publishing Company as part of the "Giselle Wyers Choral Series," and have been performed across the United States, South America, Canada, Australia, Cuba, and numerous European cities. Her latest premiere was a 30-minute choral cycle entitled And All Shall Be Well, commissioned by the Vashon Island Chorale. In 2020, four new choral works will premiere across the United States. She is also committed to mentoring scholar-writers in the field, and serves on the editorial board of ACDA’s Choral Journal.